Description

Mysimba 

Mysimba  is a weight loss medication used in patients who are classed as obese alongside diet and exercise to help aid weight loss. It is a prescription medication and must be prescribed by a registered professional.

How does Myssimba work?

Mysimba is a prescription-only weight loss drug with two key ingredients, naltrexone and bupropion. Mysimba comes in tablet form with patients usually taking 1-2 a day, with a limit of 4 per day. The tablets work by reducing your appetite so that you are satisfied eating less, the active ingredients are also thought to curb cravings, reducing the desire to eat and making weight loss more achievable. Mysimba is used to treat those with an overweight BMI of 30 or more.

How effective is Myssimba?

For a medication to be licensed for sale, there is a thorough and rigorous amount of testing which must take place. Data published for the public by The European Medicines Agency explains that Mysimba was proven to be effective in reducing body weight in 4 main studies involving approximately 4500 obese or overweight patients. Patients in the studies were given the drug or a placebo in combination with a weight loss program involving counseling and advice on diet and exercise.

The European Medicines Agency goes on to explain:

“In three of the studies, the average weight loss in patients treated with Mysimba was around 3.7 to 5.7%, compared with 1.3 to 1.9% with placebo; the proportion of Mysimba-treated patients who achieved 5% weight loss ranged from 28 to 42% compared with 12 to 14% with placebo. About 13 to 22% of those taking Mysimba achieved at least a 10% reduction in weight, while 5 to 6% of placebo-treated patients did so.

In the other study, in which patient counseling was also more intensive, the overall weight loss was greater over the study period: 8.1% with Myssimba and 4.9% with placebo. Some 46% and 30% of patients given Mysimba achieved 5 and 10% weight reductions respectively, compared with 34% and 17% respectively with placebo.

The degree of improvement with Myssimba over placebo was similar using different methods of analysis, although the benefits were smallest with the most conservative methods that assumed patients who did not complete the study would not have seen any improvement. The treatment effect was more marked in patients who completed 56 weeks of treatment, or who had lost at least 5% of their original body weight by 4 months.” A full reference can be found here.

How long does Mysimba last?

When you first start Myssimba, a single pack of 112 tablets lasts 5 weeks.

Your medicine should be taken as advised by us. When you take Mysimba you will gradually increase your dose over a four-week period until you reach what is called the maintenance dose. This is the dose at which you will continue to take Mysimba.